Custom Development and Manufacturing

Our service

From idea to molecule with enzymatic technology

Are you looking for a specific molecule, functionality or modification? We develop custom cell-free, multi-enzyme processes for your target molecule from feasibility and enzyme cascade design through process development and scale-up to manufacturing. Enzymatic synthesis runs under mild, aqueous conditions, offers high selectivity and yields molecules identical to their natural counterparts – without the complexity of whole-cell fermentation.

R&D

We are experts in ingredient design and selection, and in setting up proof-of-concept processes for the production of proteins, enzymes and sugars.

R&D equipmentR&D equipmentR&D equipment

Upstream Processing

We are your partner for recombinant enzyme production, enzyme formulation and cell-free process development from 0.5 L to 100 L scale.

Upstream processing equipmentUpstream processing equipmentUpstream processing equipment

Downstream Processing

Our purification capabilities range from micro-, ultra- and nanofiltration to chromatography. We offer crystallization as well as freeze- and spray-drying.

Downstream processing equipmentDownstream processing equipmentDownstream processing equipment

Analysis

We provide analytical capabilities to carefully analyze all products and ensure compliance with the highest quality and purity standards.

Analytical equipmentAnalytical equipmentAnalytical equipment
How we work

From your requirements to the final product

Our custom development process – one partner from the first idea to the final product, from gram to industrial scale.

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01

Research & Discovery

Starting from your requirements, we evaluate the target molecule, review literature and patents, and design a suitable enzymatic route.

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02

Wet-Lab Experiments & Development

Small-scale lab experiments deliver proof of concept, enzyme screening and first product samples.

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03

Process Development

We optimize the enzyme cascade, reaction conditions and downstream processing for yield, purity and cost-efficiency – ready for scale-up.

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04

Large-scale Production

Manufacturing of your molecule from gram quantities to industrial scale, including purification and formulation such as spray and freeze drying.

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05

Analysis & Quality Control

Analytical characterization and quality control ensure your final product meets the agreed specifications.

Industries

Custom development for three industries

  • Nutritional Ingredients

    Looking for a specific ingredient? We develop exactly the nutritional ingredient you need – from bioactive carbohydrates to rare sugars – with an enzymatic process designed for your product.

    More information
  • Actives for Personal Care

    We develop specific actives tailored precisely to your functional requirements – sustainably produced via biocatalysis and ready for your formulation.

    More information
  • Raw Material for Pharma and R&D

    Specific raw materials developed to your requirements – or targeted modifications of existing molecules – for pharmaceutical, diagnostic and research applications.

    More information

Contact us

Get in touch to find out more and work together!

innovation@primogene.bio
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